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BITEIN Research Study Details

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Principal Researcher

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Subject

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Co Workers

Description

The purpose of this study is to assess the effect of Turm Nova on gingival health when taken in the form of lozenges twice a day for three weeks and compare with subjects who have not been given Turm Nova.  The active ingredient of Turm Nova is curcumin which is very poorly absorbed through the gut. One of the best uptakes of curcumin is through the oral mucosa. Turm Nova lozenges deliver the maximum potential of curcumin using a protected patent technology.  Curcumin is known to have strong anti bacterial as well as anti inflammatory properties.  In this study an attempt is being made to see the effect of Turm Nova  on  gingivitis without any other parameters being changed and compare with a group who have not been given Turm Nova.  The scores will be recorded by the operator without being aware in which group the subject belongs, to eliminate bias.

The study would recruit 60 subjects and divide them  into two cohorts of 30 each.  An oral prophylaxis would be carried out and a full history taken and the baseline GI and PI scores would be taken.  Patients with advanced periodontal disease exhibiting more than one site with pockets > 4 mm as well as patients with purulent exudation in more than one site will not be included in the study. After initial baseline recording of the scores all subjects in both groups will be recalled after 3 weeks and the GI and PI scores recorded once again. One group will then be put on Turm  Nova twice a day.  No other change will be made in the oral hygiene methods. After a period of another 3  weeks the GI and PI scores will be again checked for both the groups and the data subjected to statistical analysis. Suggested index for recording Gingival inflammation is the Loe and Sillness Index and the Quigley Hein index for plaque scores.